Comparison of Dexmedetomidine and Dexamethasone as an Adjuvant to Bupivacaine in Onset and Interval of Supraclavicular Nerve Block

Aim: To compare duration and onset of motor sensory block by using dexmedetomidine dexamethasone as adjuvant to bupivicaine in supraclavicular brachial plexusblock. Place study: Department Anaesthesiology, Surgical Intensive Care & Pain Management, Civil Hospital, Dow University Health Sciences Karachi from 29th June 2022 December 2022. Design: Randomized controlled trial study Methodology: Sixty patientswere enrolled the that had an elective upper-limb surgery performed under anesthesia hand, wrist, forearmand elbow were allocated through randomization into two groups. Thirty patients group A treated with bupivacaine 25 ml 0.5% 8mg (2 ML) 30 B 1µg/kg (2ml). Patients observed post-anesthesiacareunitpost-surgery. Duration pain was noted patient’s first request for analgesia. Results:Themean age 34.88±9.39 years. Mean time significantly low than B. high [813.87±113.72 vs. 752.63±27.96; p=0.006] [734.13± 84.44 vs533.07±88.38;p=0.0005]. The 1st rescue analgesic increased A(p=0.0005). Practical Implication: Regional orthopedic procedures is superior general terms better postoperative relief, less central nervous system depressant effect drugs early discharge hospital. Conclusion:The prolonged cases where added longer but reduced comparison cases. Keywords: Brachial plexus block, Supraclavicular Dexmedetomidine, Dexamethasone